Primary Sclerosing Cholangitis - Current Issues in Clinical Practice
نویسندگان
چکیده
Aims: To review current issues in the diagnosis and treatment of primary sclerosing cholangitis. Methods: search of PubMed using the terms “primary sclerosing cholangitis”, “PSC”, “cholangitis” and “cholestasis”, as well as by review of current guidelines from the major international liver societies. Results: Primary sclerosing cholangitis is still a challenging condition to diagnose and manage, but newer imaging modalities like MRCP and timing of liver transplantation point the way forward.
منابع مشابه
Improving Symptoms of Primary Sclerosing Cholangitis by Iranian Traditional Medicine
Introduction: Primary Sclerosing Cholangitis (PSC) is a chronic cholestatic disease that results from the inflammation and destruction of intra- and extra-hepatic bile ducts and fibrosis which can lead to cirrhosis. The purpose of this report is to provide the clinical experience of Iranian traditional medicine with the best therapeutic effect within the shortest time. <s...
متن کاملReview article: controversies in the management of primary biliary cirrhosis and primary sclerosing cholangitis.
BACKGROUND Despite considerable advances over the last two decades in the molecular understanding of cholestasis and cholestatic liver disease, little improvement has been made in diagnostic tools and therapeutic strategies. AIMS To critically review controversial aspects of the scientific basis for common clinical practice in primary biliary cirrhosis (PBC) and primary sclerosing cholangitis...
متن کاملOccasional viewpoint Increased colorectal neoplasia in chronic ulcerative colitis complicated by primary sclerosing cholangitis: fact or fiction?
It is well accepted that patients with ulcerative colitis (UC) are at increased risk of developing colorectal carcinoma. Since 1992, several studies have examined the hypothesis that patients with concomitant primary sclerosing cholangitis (PSC) are at significantly increased risk of developing colorectal cancer or dysplasia. The size, design, end points, and populations involved in these studi...
متن کاملIncreased colorectal neoplasia in chronic ulcerative colitis complicated by primary sclerosing cholangitis: fact or fiction?
It is well accepted that patients with ulcerative colitis (UC) are at increased risk of developing colorectal carcinoma. Since 1992, several studies have examined the hypothesis that patients with concomitant primary sclerosing cholangitis (PSC) are at significantly increased risk of developing colorectal cancer or dysplasia. The size, design, end points, and populations involved in these studi...
متن کاملUpdate on primary sclerosing cholangitis.
Early studies in primary sclerosing cholangitis (PSC) were concerned with disease characterization, and were followed by epidemiological studies of PSC and clinical subsets of PSC as well as a large number of treatment trials. Recently, the molecular pathogenesis and the practical handling of the patients have received increasing attention. In the present review we aim to give an update on the ...
متن کامل